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Acute syphilitic posterior placoid chorioretinitis (ASPPC) is defined by the presence of a placoid, yellowish, often solitary lesion, typically involving the areas of the temporal vascular arcades, the juxtapapillary retina, and/or the macular region, with the lesions being present at the level of the outer retina and retinal pigment epithelium (RPE). The visual acuity may range from no light perception to 20/20. There may be associated anterior chamber inflammation and vitritis. Therapy should include antibiotics for neurosyphilis. The role of corticosteroids is controversial. HIV coinfection should always be tested for. With appropriate therapy, the prognosis seems to be good.


Acute syphilitic posterior placoid chorioretinitis HIV Penicillin Retinal pigment epithelium Syphilis

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Andonova, N., Markov, G., Zdravkov, Y., & Oscar, A. (2022). Acute Syphilitic Posterior Placoid Chorioretinitis: A Narrative Literature Review. Sriwijaya Journal of Ophthalmology, 5(2), 198-201.

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